The future of optimising health with active folate.
Folate, as 5‐methyltetrahydrofolic (5-MTHF), is an essential vitamin. Some of the essential roles of 5-MTHF in the body include:
– Normal healthy growth and development
– Cell growth and division
– Synthesis of DNA, RNA, and proteins
– Enzymatic reactions
Some of the functions of 5-MTHF:
– One-carbon metabolism
– Methylation
– Amino acid metabolism
– Purine and pyrimidine synthesis
– DNA repair
– DNA methylation
– Re-methylation of homocysteine to methionine
Some of the conditions related to folate deficiency include:
– Megaloblastic anaemia
– Peripheral neuropathy
– Cardiovascular diseases
– Hyperhomocysteineaemia
– Depression
– Cognitive dysfunction and decline
A 5,10-methylene tetrahydrofolate reductase (MTHFR) gene polymorphism negatively affects folate metabolism and represents a potential risk factor for numerous diseases, such as cardiovascular disease, hyperhomocysteinaemia, pregnancy complications, infertility, and depression.
Presented at the Natural Health Products Innovation Expo NZ in Auckland, New Zealand on 16 November 2023.
References:
McEwen B. JATMS 2023; 29(1): 24-28.
McEwen B. Adv Integ Med 2016; 3(3): 79-81.
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For informational purposes only. It is not intended to be a substitute for professional medical advice. Always talk to a health professional. Follow the directions for use.